Jul 11, 2017

Update from the Equine Medical Research Committee

An x-ray showing carpal arthritis. USEA Photo.

The funding from USEA’s Equine Medical Research Fund is generating some RESULTS! Since 2013, every starter at a USEA event pays $1 towards equine medical research. This fee was created in order to address that underfunding of equine research in the United States. The USEA partnered with the Morris Animal Foundation to help select and track studies relevant to sport horses and to general equine health. Here are summaries of the results of two of the studies we funded.

RESULTS: Investigators advance cell-based therapy research for horses

Dr. Emma Adam and her research colleagues at the University of Kentucky analyzed the unique biology of equine cartilage cells. Presently, cell-based therapies cannot fully repair damaged cartilage and restore joint surface integrity. A major limiting factor has been scientists’ inability to produce robust cartilage cells for cell-based therapies that retain their original traits and characteristics when grown in culture, and are fully functional when administered to equine patients with damaged joints or degenerative joint diseases, such as osteoarthritis.

Tackling this issue, Dr. Adam and her team compared different cartilaginous tissues from horses. They isolated and sequenced genetic material from these tissues to see which genes are active and how the expression of different genes distinguishes different cartilage types. Their investigation achieved two important results. The researchers identified: 1) specific genes that can help evaluate the performance of therapeutic stem cells. (Currently, the benefits of cell-based therapies are hard to track in equine patients); and 2) novel cell types that warrant further study as potential candidate cells for cell-based therapies to repair articular cartilage in synovial joints.

Healthy cartilage absorbs shock and reduces friction in joints when a horse moves. An injury that damages joints and surrounding cartilage can lead to pain, loss of mobility and osteoarthritis. Researchers hope that emerging cell-based therapies, under the broad heading of regenerative medicine, will eventually help repair these types of injuries. Dr. Adam’s study provides new data for the search for robust cell-based therapies that will help restore articular cartilage function in horses with damaged joints associated with osteoarthritis and other degenerative joint diseases.


Taking x-rays of the hock. USEA Photo.

RESULTS: Researchers Verify Genetic Mutations for Osteochondrosis Risk in Horses

Osteochondrosis (OC) is a developmental orthopedic condition commonly diagnosed in young horses. The disease is caused by abnormal cartilage development resulting in the formation of lesions in joints, with the joints of the hind limbs most commonly affected. Osteochondrosis can be a mild to severe disease, but almost always requires surgical correction to prevent further joint damage. The disease results from a complex interplay of genetic and environmental factors. Attempts to influence the environment have had limited success in controlling the disease.

Understanding the genetics behind osteochondrosis represents the best chance for OC prevention. Some horse breeds, including Standardbreds, Warmbloods and Thoroughbreds, have a higher incidence of OC, emphasizing the genetic component of the disease. Researchers from the University of Illinois and the University of Minnesota identified several genetic mutations associated with OC in a population of yearling horses born and raised on a single breeding farm in the United States. To add statistical value to their findings, the team validated their data in a second, unrelated population of horses from Norway. The results of this study were a first step toward the team’s long-term goal of creating a genetic risk model for osteochondrosis that could be applied to individual horses.

Defining the genetic and biomechanical factors in OC development will improve early intervention to help reduce the risk of clinical disease in individual horses and high-risk breeds. The new information gained from these investigations will help guide management changes and also aid in informed breeding decisions to reduce disease incidence in horses.

The EMRF Committee received several thank you letters from the last batch of researchers who received USEA funding. The most fun letter was this one, from fellow eventer Dr. Stephanie Valberg! (The committee had no knowledge that the researcher was an eventer when the funding decision was made. But it’s great fun to find that out!)


Dr. Stephanie Valberg and her warmblood gelding, Cajun. Photo courtesy of Dr. Stephanie Valberg.

“Thank you so much for supporting our research grant to investigate whether horse’s underlying susceptibility to tying up is due to a unique recently discovered protein called sarcolipin. I am really excited about this project and energized to work with such a distinguished group of researchers as Dr. Dave Thomas and his colleagues in Minnesota. Collaborations where you can focus the insights of renowned basic scientists like Dave on vexing problems that affect horses can be really powerful. The project is going well.

I really appreciate the support of the USEA. I am myself a member and longtime eventer with a pause in the middle for school and kids. I currently have a young Warmblood that I have been competing with at Beginner Novice. We moved from Minnesota to Michigan this year and his dressage and stadium have been terrific but it has been a real challenge to get him (and myself) to settle in and competing on new cross-country venues. I am hoping for better things next season and a bump up to Novice! One of the things I love about the sport is that it is so challenging. It’s a good mind set for doing equine research."

Jul 02, 2024 Educational Activities

USEA Educational Activity Highlight: Sherwood Forest Hunter Pace | Sherwood Oregon | July 13, 2024

What’s a Hunter Pace? The Sherwood Forest Equestrian Center's Hunter Pace is a cross-country-style course around Sherwood Forest over various natural obstacles/terrain. The course ends with a final treat for riders to take in stunning views of Mt. Hood with a loop through the old Far Hill Farms field. The beginning of the course will first start with a warm-up loop around show jumping obstacles in the outdoor ring at Sherwood Forest and then riders will continue directly onto the course. Sign up as a solo rider, pair, or team.

Jul 02, 2024 Profile

No Longer Dreaming: Claire Allen's Goal of Qualifying for USEF Eventing Young Rider Championship is Now Reality

Claire Allen remembers when she was 11 years old, having just made the switch from the hunter/jumper ring to three-day eventing. She told her new eventing trainer that her goal was to one day compete in the United States Equestrian Federation’s Eventing Young Rider Championships.

Jul 01, 2024 Competitions

Alliston’s Busy Weekend, Braitling’s Reuniting with Five-Star Mount, & Kalkman’s Advanced Victory Highlight Twin Rivers Summer H.T.

As he was finishing tacking up his horse in preparation to navigate the cross-country course at the 2024 Twin Rivers Summer Horse Trials, James Alliston expressed concern about navigating the 101 Freeway. That’s because as soon as he crossed the finish line aboard Intermediate level winner Addyson (Ampere x Nickerbocker) at 10:38 a.m. on Saturday—his fifth cross-country round of the morning with three at Preliminary and two at Intermediate—the West Coast-based five-star rider had to drive 185 miles on the 101 Freeway from Twin Rivers Ranch in Paso Robles, California, to San Francisco International Airport to catch a 4:35 p.m. flight to Frankfurt, Germany.

Jul 01, 2024 Education

USEA Podcast #364: All Your Grooming Questions Answered

There is so much more to proper grooming than keeping your horse picture-perfect for the horse inspection. Good grooming practices are critical to proper horse management, no matter if you are planning for your next FEI appearance or your Starter level debut. To help you maximize your knowledge of grooming practices, we opened up the opportunity for USEA members to submit any questions they might have on our Instagram and Facebook stories. In this week's episode, Host Nicole Brown sits down with three of the highest-regarded grooms in this industry, Max Corcoran, Emma Ford, and Stephanie Simpson, and asks them all of your questions and more to help you perfect the art of grooming.

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